The effect of Raphanus sativus and Pachyrhizus erosus juice combination on the ethanol-induced gastric of mice

Gastric ulcers can be caused by active inflammation due to impaired mucosal integrity, which causes local or widespread lesions. occur the use of ethanol, has a effect on gastric. Therefore, continuous consumption ethanol damage gastric cells. Raphanus sativus  and Pachyrhizus erosus contain flavonoids, are well-known reduce stomach acid as curative agent. The objective this study is see of sativus juice preventive agent alcohol-induced in mice ( Mus musculus ). A combination and was given at dose 100, 300, 600 mg/kgBW. Specifically, 300 mg/kgBW, positive control included using sucralfate. treatment carried out for 12 days, 1 hour after last day treatment, 20 ml/kgBW induction 24 hours animals were dissected. results showed that index value normal group, negative control, orally mg/kgBW sucralfate control) 0; 4.00; 1.00; 1.33; 2.33; 2.67; 0 2.00. histopathological analysis also improvement fed with juice. it inferred number ulcers, increase ratio protection, repair cells histopathology. Additionally, giving single more significant improvement.